A spider silk-derived solubility domain inhibits nuclear and cytosolic protein aggregation in human cells

Due to the inherent toxicity of protein aggregates, the propensity of natural, functional amyloidogenic proteins to aggregate must be tightly controlled to avoid negative consequences on cellular viability. The importance of controlled aggregation in biological processes is illustrated by spidroins,...

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Detalles Bibliográficos
Autores principales: Schellhaus, Anna Katharina, Xu, Shanshan, Gierisch, Maria E., Vornberger, Julia, Johansson, Jan, Dantuma, Nico P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135726/
https://www.ncbi.nlm.nih.gov/pubmed/35618760
http://dx.doi.org/10.1038/s42003-022-03442-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135726/
https://www.ncbi.nlm.nih.gov/pubmed/35618760
http://dx.doi.org/10.1038/s42003-022-03442-5

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