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A spider silk-derived solubility domain inhibits nuclear and cytosolic protein aggregation in human cells
Due to the inherent toxicity of protein aggregates, the propensity of natural, functional amyloidogenic proteins to aggregate must be tightly controlled to avoid negative consequences on cellular viability. The importance of controlled aggregation in biological processes is illustrated by spidroins,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135726/ https://www.ncbi.nlm.nih.gov/pubmed/35618760 http://dx.doi.org/10.1038/s42003-022-03442-5 |