Different DNA methylome, transcriptome and histological features in uterine fibroids with and without MED12 mutations

Somatic mutations in Mediator complex subunit 12 (MED12m) have been reported as a biomarker of uterine fibroids (UFs). However, the role of MED12m is still unclear in the pathogenesis of UFs. Therefore, we investigated the differences in DNA methylome, transcriptome, and histological features betwee...

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Detalles Bibliográficos
Autores principales: Maekawa, Ryo, Sato, Shun, Tamehisa, Tetsuro, Sakai, Takahiro, Kajimura, Takuya, Sueoka, Kotaro, Sugino, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135739/
https://www.ncbi.nlm.nih.gov/pubmed/35618793
http://dx.doi.org/10.1038/s41598-022-12899-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135739/
https://www.ncbi.nlm.nih.gov/pubmed/35618793
http://dx.doi.org/10.1038/s41598-022-12899-7

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