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Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and weight regain in mice

Within adipose tissue (AT), immune cells and parenchymal cells closely interact creating a complex microenvironment. In obesity, immune cell derived inflammation contributes to insulin resistance and glucose intolerance. Diet-induced weight loss improves glucose tolerance; however, weight regain fur...

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Detalles Bibliográficos
Autores principales: Cottam, Matthew A., Caslin, Heather L., Winn, Nathan C., Hasty, Alyssa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135744/
https://www.ncbi.nlm.nih.gov/pubmed/35618862
http://dx.doi.org/10.1038/s41467-022-30646-4