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Enantioselective alkylative cross-coupling of unactivated aromatic C–O electrophiles

Nonpolar alkyl moieties, especially methyl group, are frequently used to modify bioactive molecules during lead optimization in medicinal chemistry. Thus transition-metal catalyzed alkylative cross-coupling reactions by using readily available and environmentally benign C–O electrophiles have been e...

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Detalles Bibliográficos
Autores principales: Zhang, Zishuo, Zhang, Jintong, Gao, Quan, Zhou, Yu, Yang, Mingyu, Cao, Haiqun, Sun, Tingting, Luo, Gen, Cao, Zhi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135759/
https://www.ncbi.nlm.nih.gov/pubmed/35618745
http://dx.doi.org/10.1038/s41467-022-30693-x