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The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase

The pleiotropic function of long noncoding RNAs is well recognized, but their direct role in governing metabolic homeostasis is less understood. Here, we describe a human adipocyte-specific lncRNA, ADIPINT, that regulates pyruvate carboxylase, a pivotal enzyme in energy metabolism. We developed an a...

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Detalles Bibliográficos
Autores principales: Kerr, Alastair G., Wang, Zuoneng, Wang, Na, Kwok, Kelvin H. M., Jalkanen, Jutta, Ludzki, Alison, Lecoutre, Simon, Langin, Dominique, Bergo, Martin O., Dahlman, Ingrid, Mim, Carsten, Arner, Peter, Gao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135762/
https://www.ncbi.nlm.nih.gov/pubmed/35618718
http://dx.doi.org/10.1038/s41467-022-30620-0