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Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

BACKGROUND: Concomitant inhibition of vascular endothelial growth factor (VEGF) and programmed cell death protein 1 (PD-1) or its ligand PD-L1 is a standard of care for patients with advanced hepatocellular carcinoma (HCC), but only a minority of patients respond, and responses are usually transient...

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Detalles Bibliográficos
Autores principales: Mi, Haoyang, Ho, Won Jin, Yarchoan, Mark, Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136005/
https://www.ncbi.nlm.nih.gov/pubmed/35634309
http://dx.doi.org/10.3389/fimmu.2022.892250