Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling

Adult hippocampal neurogenesis (AHN) is involved in learning and memory as well as regulation of mood. Binge ethanol reduces AHN, though the mechanism is unknown. Microglia in the neurogenic niche are important regulators of AHN, and ethanol promotes proinflammatory microglia activation. We recently...

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Detalles Bibliográficos
Autores principales: Zou, Jian, Walter, T. Jordan, Barnett, Alexandra, Rohlman, Aaron, Crews, Fulton T., Coleman, Leon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136051/
https://www.ncbi.nlm.nih.gov/pubmed/35634322
http://dx.doi.org/10.3389/fimmu.2022.866073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136051/
https://www.ncbi.nlm.nih.gov/pubmed/35634322
http://dx.doi.org/10.3389/fimmu.2022.866073

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