Cargando…

Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase

Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and occurs predominantly in patients with underlying chronic liver diseases. Over the past decade, human ornithine aminotransferase (hOAT), which is an enzyme that catalyzes the metabolic conversion of ornithine into an in...

Descripción completa

Detalles Bibliográficos
Autores principales: Butrin, Arseniy, Butrin, Anastassiya, Wawrzak, Zdzislaw, Moran, Graham R., Liu, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136103/
https://www.ncbi.nlm.nih.gov/pubmed/35460691
http://dx.doi.org/10.1016/j.jbc.2022.101969