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Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and occurs predominantly in patients with underlying chronic liver diseases. Over the past decade, human ornithine aminotransferase (hOAT), which is an enzyme that catalyzes the metabolic conversion of ornithine into an in...
Autores principales: | Butrin, Arseniy, Butrin, Anastassiya, Wawrzak, Zdzislaw, Moran, Graham R., Liu, Dali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136103/ https://www.ncbi.nlm.nih.gov/pubmed/35460691 http://dx.doi.org/10.1016/j.jbc.2022.101969 |
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