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Lysophosphatidylcholine acyltransferase 1 controls mitochondrial reactive oxygen species generation and survival of retinal photoreceptor cells

Due to their high energy demands and characteristic morphology, retinal photoreceptor cells require a specialized lipid metabolism for survival and function. Accordingly, dysregulation of lipid metabolism leads to the photoreceptor cell death and retinal degeneration. Mice bearing a frameshift mutat...

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Detalles Bibliográficos
Autores principales: Nagata, Katsuyuki, Hishikawa, Daisuke, Sagara, Hiroshi, Saito, Masamichi, Watanabe, Sumiko, Shimizu, Takao, Shindou, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136105/
https://www.ncbi.nlm.nih.gov/pubmed/35452679
http://dx.doi.org/10.1016/j.jbc.2022.101958