Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase

The posttranslational regulation of the neuronal proteome is critical for brain homeostasis but becomes dysregulated in the aged or diseased brain, in which abnormal posttranslational modifications (PTMs) are frequently observed. While the full extent of modified substrates that comprise the “PTM-om...

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Detalles Bibliográficos
Autores principales: Tabassum, Zarin, Tseng, Jui-Heng, Isemann, Camryn, Tian, Xu, Chen, Youjun, Herring, Laura E., Cohen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136110/
https://www.ncbi.nlm.nih.gov/pubmed/35469920
http://dx.doi.org/10.1016/j.jbc.2022.101977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136110/
https://www.ncbi.nlm.nih.gov/pubmed/35469920
http://dx.doi.org/10.1016/j.jbc.2022.101977

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