Enhanced Orai1-mediated store-operated Ca(2+) channel/calpain signaling contributes to high glucose-induced podocyte injury

Podocyte injury induced by hyperglycemia is the main cause of kidney dysfunction in diabetic nephropathy. However, the underlying mechanism is unclear. Store-operated Ca(2+) entry (SOCE) regulates a diversity of cellular processes in a variety of cell types. Calpain, a Ca(2+)-dependent cysteine prot...

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Detalles Bibliográficos
Autores principales: Tao, Yu, Chaudhari, Sarika, Shotorbani, Parisa Yazdizadeh, Ding, Yanfeng, Chen, Zhenglan, Kasetti, Ramesh, Zode, Gulab, Ma, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136128/
https://www.ncbi.nlm.nih.gov/pubmed/35490782
http://dx.doi.org/10.1016/j.jbc.2022.101990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136128/
https://www.ncbi.nlm.nih.gov/pubmed/35490782
http://dx.doi.org/10.1016/j.jbc.2022.101990

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