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Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling

Intestinal fibrosis is considered to be a chronic complication of inflammatory bowel disease (IBD) and seriously threatening human health. Effective medical therapies or preventive measures are desirable but currently unavailable. Metformin has been proved to have a satisfactory anti-inflammatory ef...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wang, Zhi, Yang, Huiping, Chen, Shuze, Zheng, Dekai, Liu, Xiuying, Jiang, Qinrui, Chen, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136141/
https://www.ncbi.nlm.nih.gov/pubmed/35645830
http://dx.doi.org/10.3389/fphar.2022.887497