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Förster Resonance Energy Transfer-Based Single-Cell Imaging Reveals Piezo1-Induced Ca(2+) Flux Mediates Membrane Ruffling and Cell Survival

A mechanosensitive ion channel, Piezo1 induces non-selective cation flux in response to various mechanical stresses. However, the biological interpretation and underlying mechanisms of cells resulting from Piezo1 activation remain elusive. This study elucidates Piezo1-mediated Ca(2+) influx driven b...

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Detalles Bibliográficos
Autores principales: Kim, Heon-Su, Suh, Jung-Soo, Jang, Yoon-Kwan, Ahn, Sang-Hyun, Choi, Gyu-Ho, Yang, Jin-Young, Lim, Gah-Hyun, Jung, Youngmi, Jiang, Jie, Sun, Jie, Suk, Myungeun, Wang, Yingxiao, Kim, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136143/
https://www.ncbi.nlm.nih.gov/pubmed/35646889
http://dx.doi.org/10.3389/fcell.2022.865056