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The CSF Vancomycin Concentration in Patients With Post-operative Intracranial Infection Can Be Predicted by the WBCs to Total Cells Ratio and the Serum Trough Concentration

BACKGROUND: The pharmacokinetics of vancomycin in cerebrospinal fluid (CSF) is an important basis for evaluating the bactericidal effect. The accuracy of using serum vancomycin concentrations only to estimate the CSF concentrations remains controversial, may lead to underdosing. OBJECTIVES: The aims...

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Detalles Bibliográficos
Autores principales: Fan, Ming-Chao, Sun, Jia-Lin, Sun, Jian, Ma, Jun-Wei, Wang, Nian, Fang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136157/
https://www.ncbi.nlm.nih.gov/pubmed/35645947
http://dx.doi.org/10.3389/fneur.2022.893089