Dapagliflozin Attenuates Myocardial Fibrosis by Inhibiting the TGF-β1/Smad Signaling Pathway in a Normoglycemic Rabbit Model of Chronic Heart Failure

Recent studies have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors play a beneficial role for normoglycemic patients with heart failure (HF). However, the underlying mechanism remains largely unexplored. In the present study, we aimed to investigate the cardioprotective effect of SGLT2...

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Detalles Bibliográficos
Autores principales: Chen, Xuefeng, Yang, Qian, Bai, Wenlou, Yao, Wenjing, Liu, Litian, Xing, Yuanyuan, Meng, Cunliang, Qi, Peng, Dang, Yi, Qi, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136228/
https://www.ncbi.nlm.nih.gov/pubmed/35645838
http://dx.doi.org/10.3389/fphar.2022.873108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136228/
https://www.ncbi.nlm.nih.gov/pubmed/35645838
http://dx.doi.org/10.3389/fphar.2022.873108

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