Cargando…

Border cell polarity and collective migration require the spliceosome component Cactin

Border cells are an in vivo model for collective cell migration. Here, we identify the gene cactin as essential for border cell cluster organization, delamination, and migration. In Cactin-depleted cells, the apical proteins aPKC and Crumbs (Crb) become abnormally concentrated, and overall cluster p...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Guangxia, Guo, Li, Montell, Denise J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136304/
https://www.ncbi.nlm.nih.gov/pubmed/35612426
http://dx.doi.org/10.1083/jcb.202202146