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Border cell polarity and collective migration require the spliceosome component Cactin
Border cells are an in vivo model for collective cell migration. Here, we identify the gene cactin as essential for border cell cluster organization, delamination, and migration. In Cactin-depleted cells, the apical proteins aPKC and Crumbs (Crb) become abnormally concentrated, and overall cluster p...
Autores principales: | Miao, Guangxia, Guo, Li, Montell, Denise J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136304/ https://www.ncbi.nlm.nih.gov/pubmed/35612426 http://dx.doi.org/10.1083/jcb.202202146 |
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