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Treatment With Nimodipine or FK506 After Facial Nerve Repair Neither Improves Accuracy of Reinnervation Nor Recovery of Mimetic Function in Rats

PURPOSE: Nimodipine and FK506 (Tacrolimus) are drugs that have been reported to accelerate peripheral nerve regeneration. We therefore tested these substances aiming to improve the final functional outcome of motoric reinnervation after facial nerve injury. METHODS: In 18 female rats, the transected...

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Detalles Bibliográficos
Autores principales: Barham, Mohammed, Streppel, Michael, Guntinas-Lichius, Orlando, Fulgham-Scott, Nicole, Vogt, Johannes, Neiss, Wolfram F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136327/
https://www.ncbi.nlm.nih.gov/pubmed/35645727
http://dx.doi.org/10.3389/fnins.2022.895076