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In vivo gain-of-function cDNA library screening for colonization genes in a mouse model of pulmonary metastasis

We provide a protocol for gain-of-function (GOF) cDNA screen of genes that foster cancer cell colonization of secondary tissues, the last and most lethal step of the metastasis cascade. We present techniques for cDNA viral library preparation and delivery leading up to the recovery of colonization-p...

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Detalles Bibliográficos
Autores principales: Tu, Zhenbo, Karnoub, Antoine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136352/
https://www.ncbi.nlm.nih.gov/pubmed/35634360
http://dx.doi.org/10.1016/j.xpro.2022.101413