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The monocyte activation test detects potentiated cytokine release resulting from the synergistic effect of endotoxin and non-endotoxin pyrogens

Pyrogens are classified in two groups, endotoxin pyrogens and non-endotoxin pyrogens (NEPs). The presence of either in parenteral pharmaceuticals or medical devices can cause severe harm to subjects, and when occurring in combination, synergistic potentiation effects can occur. As the standard in vi...

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Detalles Bibliográficos
Autores principales: Solati, Shabnam, Zhang, Ting, Timman, Shahrzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136467/
https://www.ncbi.nlm.nih.gov/pubmed/35491666
http://dx.doi.org/10.1177/17534259221097948