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Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL‐6 trans‐signalling

OBJECTIVES: This study investigated the specific molecular mechanism and the roles of extracellular matrix protein Spondin 1 (SPON1) in the development of pancreatic ductal adenocarcinoma (PDAC). MATERIALS AND METHODS: The expression pattern and clinical relevance of SPON1 was determined in GEO, Ren...

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Detalles Bibliográficos
Autores principales: Huo, Yanmiao, Yang, Jian, Zheng, Jiahao, Xu, Dapeng, Yang, Minwei, Tao, Lingye, Yao, Hongfei, Fu, Xueliang, Yang, Jianyu, Liu, Dejun, Hua, Rong, Zhang, Junfeng, Sun, Yongwei, Hu, Lipeng, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136514/
https://www.ncbi.nlm.nih.gov/pubmed/35487760
http://dx.doi.org/10.1111/cpr.13237