Cargando…

Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL‐6 trans‐signalling

OBJECTIVES: This study investigated the specific molecular mechanism and the roles of extracellular matrix protein Spondin 1 (SPON1) in the development of pancreatic ductal adenocarcinoma (PDAC). MATERIALS AND METHODS: The expression pattern and clinical relevance of SPON1 was determined in GEO, Ren...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huo, Yanmiao, Yang, Jian, Zheng, Jiahao, Xu, Dapeng, Yang, Minwei, Tao, Lingye, Yao, Hongfei, Fu, Xueliang, Yang, Jianyu, Liu, Dejun, Hua, Rong, Zhang, Junfeng, Sun, Yongwei, Hu, Lipeng, Liu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136514/ https://www.ncbi.nlm.nih.gov/pubmed/35487760 http://dx.doi.org/10.1111/cpr.13237

Ejemplares similares

Molecular markers associated with perineural invasion in pancreatic ductal adenocarcinoma
por: Zhang, Junfeng, et al.
Publicado: (2020)

High expression of DDR1 is associated with the poor prognosis in Chinese patients with pancreatic ductal adenocarcinoma
por: Huo, Yanmiao, et al.
Publicado: (2015)

DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jianyu, et al.
Publicado: (2019)

Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma
por: Yang, Jianyu, et al.
Publicado: (2021)

Transcription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1
por: Jiang, Yongsheng, et al.
Publicado: (2019)

GJB3 promotes pancreatic cancer liver metastasis by enhancing the polarization and survival of neutrophil
por: Huo, Yanmiao, et al.
Publicado: (2022)

Endoplasmic Reticulum stress-dependent expression of ERO1L promotes aerobic glycolysis in Pancreatic Cancer
por: Zhang, Junfeng, et al.
Publicado: (2020)

Tumor-derived exosomal HOTAIRM1 regulates SPON2 in CAFs to promote progression of lung adenocarcinoma
por: Chen, Zhipeng, et al.
Publicado: (2022)

SPON1 is an independent prognostic biomarker for ovarian cancer
por: Miyakawa, Ryoya, et al.
Publicado: (2023)

SponDT (Spondylodiscitis Diagnosis and Treatment): spondylodiscitis scoring system
por: Homagk, Lars, et al.
Publicado: (2019)

The Association Between Frailty and Parkinson’s Disease in the ReSPOnD Trial
por: Smith, Natalie, et al.
Publicado: (2021)

Knockdown of SPON2 inhibits the growth of triple-negative breast cancer
por: Hu, Xueyi, et al.
Publicado: (2023)

Comprehensive analysis of the oncogenic and immunological role of SPON2 in human tumors
por: Tang, Jiali, et al.
Publicado: (2023)

ERO1L Promotes Hepatic Metastasis through Activating Epithelial-Mesenchymal Transition (EMT) in Pancreatic Cancer
por: Yang, JianYu, et al.
Publicado: (2021)

Spon's estimating costs guide to electrical works: unit rates and project costs
por: Spain, Bryan
Publicado: (2007)

F-Spondin/spon1b Expression Patterns in Developing and Adult Zebrafish
por: Akle, Veronica, et al.
Publicado: (2012)

IL2RA is a prognostic indicator and correlated with immune characteristics of pancreatic ductal adenocarcinoma
por: Fan, Liwen, et al.
Publicado: (2022)

Spondin-2 (SPON2), a More Prostate-Cancer-Specific Diagnostic Biomarker
por: Qian, Xiaolong, et al.
Publicado: (2012)

Patterns of spon1b:GFP expression during early zebrafish brain development
por: Agudelo-Dueñas, Nathalie, et al.
Publicado: (2020)

Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC
por: Huang, Chengmei, et al.
Publicado: (2021)

SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer
por: Kang, Hyeon-Gu, et al.
Publicado: (2020)

Screening of radiotracer for diagnosis of colorectal cancer liver metastasis based on MACC1-SPON2
por: Jiang, Hao, et al.
Publicado: (2021)

Corrigendum: Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

FOXO3 regulates Smad3 and Smad7 through SPON1 circular RNA to inhibit idiopathic pulmonary fibrosis
por: Li, Hailong, et al.
Publicado: (2023)

Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma
por: Fu, Xue-Liang, et al.
Publicado: (2016)

The role of epithelial-mesenchymal transition and autophagy in pancreatic ductal adenocarcinoma invasion
por: Yang, Jian, et al.
Publicado: (2023)

Serum Nardilysin as a Prognostic Biomarker in Pancreatic Ductal Adenocarcinoma
por: Xu, Yongfeng, et al.
Publicado: (2022)

Validation of IL-7R as an Immunological Biomarker for Human Pancreatic Ductal Adenocarcinoma
por: Jang, Sung-Ill, et al.
Publicado: (2022)

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis
por: Li, Nan, et al.
Publicado: (2020)

FAM84B, amplified in pancreatic ductal adenocarcinoma, promotes tumorigenesis through the Wnt/β-catenin pathway
por: Zhang, Xin, et al.
Publicado: (2020)

Positive Crosstalk Between Hedgehog and NF-κB Pathways Is Dependent on KRAS Mutation in Pancreatic Ductal Adenocarcinoma
por: Wang, Yuqiong, et al.
Publicado: (2021)

SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults
por: Fernandez, Shane, et al.
Publicado: (2021)

Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma
por: Zhang, Tianyi, et al.
Publicado: (2022)

KRAS-related noncoding RNAs in pancreatic ductal adenocarcinoma
por: Yu, Shuang-Ni, et al.
Publicado: (2016)

Alteration of tumor-associated macrophage subtypes mediated by KRT6A in pancreatic ductal adenocarcinoma
por: Zhang, Junfeng, et al.
Publicado: (2020)

Is there a CDKN2A-centric network in pancreatic ductal adenocarcinoma?
por: Wu, Chu, et al.
Publicado: (2020)

Corrigendum: Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis
por: Li, Nan, et al.
Publicado: (2021)

Estimating Metastatic Risk of Pancreatic Ductal Adenocarcinoma at Single-Cell Resolution
por: Chen, Sina, et al.
Publicado: (2022)

Interventional Nanotheranostics of Pancreatic Ductal Adenocarcinoma
por: Li, Junjie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_08ehtte6lt68gti5ojggnhdefb