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Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling

OBJECTIVES: To explore the role of DNA methyltransferase 1 (DNMT1) in the development of auditory system using zebrafish as experimental model. METHODS: Morpholino oligonucleotide was used to induce Dnmt1 deficiency. RNA sequencing, in situ hybridization (ISH), whole genomic bisulfide sequencing (WG...

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Detalles Bibliográficos
Autores principales: Tang, Dongmei, Zheng, Shimei, Zheng, Zhiwei, Liu, Chang, Zhang, Jiner, Yan, Renchun, Wu, Cheng, Zuo, Na, Wu, Lijuan, Xu, Hongfei, Liu, Shaofeng, He, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136517/
https://www.ncbi.nlm.nih.gov/pubmed/35352419
http://dx.doi.org/10.1111/cpr.13225