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Self-assembling, pH-responsive nanoflowers for inhibiting PAD4 and neutrophil extracellular trap formation and improving the tumor immune microenvironment

Self-assembling carrier-free nanodrugs are attractive agents because they accumulate at tumor by an enhanced permeability and retention (EPR) effect without introduction of inactive substances, and some nanodrugs can alter the immune environment. We synthesized a peptidyl arginine deiminase 4 (PAD4)...

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Detalles Bibliográficos
Autores principales: Zhu, Di, Lu, Yu, Gui, Lin, Wang, Wenjing, Hu, Xi, Chen, Su, Wang, Yanming, Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136569/
https://www.ncbi.nlm.nih.gov/pubmed/35646534
http://dx.doi.org/10.1016/j.apsb.2021.11.006