A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target

Target identification of bioactive compounds is important for understanding their mechanisms of action and provides critical insights into their therapeutic utility. While it remains a challenge, unbiased chemoproteomics strategy using clickable photoaffinity probes is a useful and validated approac...

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Detalles Bibliográficos
Autores principales: Martín-Acosta, Pedro, Meng, Qianli, Klimek, John, Reddy, Ashok P., David, Larry, Petrie, Stefanie Kaech, Li, Bingbing X., Xiao, Xiangshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136574/
https://www.ncbi.nlm.nih.gov/pubmed/35646545
http://dx.doi.org/10.1016/j.apsb.2021.12.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136574/
https://www.ncbi.nlm.nih.gov/pubmed/35646545
http://dx.doi.org/10.1016/j.apsb.2021.12.008

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