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A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target
Target identification of bioactive compounds is important for understanding their mechanisms of action and provides critical insights into their therapeutic utility. While it remains a challenge, unbiased chemoproteomics strategy using clickable photoaffinity probes is a useful and validated approac...
Autores principales: | Martín-Acosta, Pedro, Meng, Qianli, Klimek, John, Reddy, Ashok P., David, Larry, Petrie, Stefanie Kaech, Li, Bingbing X., Xiao, Xiangshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136574/ https://www.ncbi.nlm.nih.gov/pubmed/35646545 http://dx.doi.org/10.1016/j.apsb.2021.12.008 |
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