Design of a highly potent GLP-1R and GCGR dual-agonist for recovering hepatic fibrosis

Currently, there is still no effective curative treatment for the development of late-stage liver fibrosis. Here, we have illustrated that TB001, a dual glucagon-like peptide-1 receptor/glucagon receptor (GLP-1R/GCGR) agonist with higher affinity towards GCGR, could retard the progression of liver f...

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Detalles Bibliográficos
Autores principales: Song, Nazi, Xu, Hongjiao, Liu, Jiahua, Zhao, Qian, Chen, Hui, Yan, Zhibin, Yang, Runling, Luo, Zhiteng, Liu, Qi, Ouyang, Jianmei, Wu, Shuohan, Luo, Suijia, Ye, Shuyin, Lin, Runfeng, Sun, Xi, Xie, Junqiu, Lan, Tian, Wu, Zhongdao, Wang, Rui, Jiang, Xianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136578/
https://www.ncbi.nlm.nih.gov/pubmed/35646543
http://dx.doi.org/10.1016/j.apsb.2021.12.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136578/
https://www.ncbi.nlm.nih.gov/pubmed/35646543
http://dx.doi.org/10.1016/j.apsb.2021.12.016

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