Inhibition of intracellular proton-sensitive Ca(2+)-permeable TRPV3 channels protects against ischemic brain injury

Ischemic brain stroke is pathologically characterized by tissue acidosis, sustained calcium entry and progressive cell death. Previous studies focusing on antagonizing N-methyl-d-aspartate (NMDA) receptors have failed to translate any clinical benefits, suggesting a non-NMDA mechanism involved in th...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoling, Zhang, Jingliang, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136580/
https://www.ncbi.nlm.nih.gov/pubmed/35646518
http://dx.doi.org/10.1016/j.apsb.2022.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136580/
https://www.ncbi.nlm.nih.gov/pubmed/35646518
http://dx.doi.org/10.1016/j.apsb.2022.01.001

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