Cargando…

Inhibition of intracellular proton-sensitive Ca(2+)-permeable TRPV3 channels protects against ischemic brain injury

Ischemic brain stroke is pathologically characterized by tissue acidosis, sustained calcium entry and progressive cell death. Previous studies focusing on antagonizing N-methyl-d-aspartate (NMDA) receptors have failed to translate any clinical benefits, suggesting a non-NMDA mechanism involved in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xiaoling, Zhang, Jingliang, Wang, KeWei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136580/ https://www.ncbi.nlm.nih.gov/pubmed/35646518 http://dx.doi.org/10.1016/j.apsb.2022.01.001

Ejemplares similares

Purinergic Activation of Ca(2+)-Permeable TRPV4 Channels Is Essential for Mechano-Sensitivity in the Aldosterone-Sensitive Distal Nephron
por: Mamenko, Mykola, et al.
Publicado: (2011)

Blockade of TRPV channels by intracellular spermine
por: Maksaev, Grigory, et al.
Publicado: (2023)

Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
por: Wang, Haiyuan, et al.
Publicado: (2020)

Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol
por: Niu, Canyang, et al.
Publicado: (2022)

Activation of the mechanosensitive Ca(2+) channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics
por: Lu, Qing, et al.
Publicado: (2020)

Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations
por: Cui, Yuanyuan, et al.
Publicado: (2012)

Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus
por: Qi, Hang, et al.
Publicado: (2022)

Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells
por: Hisanaga, Etsuko, et al.
Publicado: (2009)

The protective role of selenium against dental amalgam-induced intracellular oxidative toxicity through the TRPV1 channel in DBTRG glioblastoma cells
por: CEYHAN, Derya, et al.
Publicado: (2021)

Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold
por: Cao, Xu, et al.
Publicado: (2014)

Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels
por: Yu, Yi, et al.
Publicado: (2014)

Intracellular Helix-Loop-Helix Domain Modulates Inactivation Kinetics of Mammalian TRPV5 and TRPV6 Channels
por: Flores-Aldama, Lisandra, et al.
Publicado: (2023)

Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia
por: Hamilton, Nicola B., et al.
Publicado: (2016)

Correction: Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels
Publicado: (2015)

MCAs in Arabidopsis are Ca(2+)-permeable mechanosensitive channels inherently sensitive to membrane tension
por: Yoshimura, Kenjiro, et al.
Publicado: (2021)

Ca(2+) Signaling by TRPV4 Channels in Respiratory Function and Disease
por: Rajan, Suhasini, et al.
Publicado: (2021)

Hysteresis of gating underlines sensitization of TRPV3 channels
por: Liu, Beiying, et al.
Publicado: (2011)

Engineering vanilloid-sensitivity into the rat TRPV2 channel
por: Zhang, Feng, et al.
Publicado: (2016)

Differential Regulation of Proton-Sensitive Ion Channels by Phospholipids: A Comparative Study between ASICs and TRPV1
por: Kweon, Hae-Jin, et al.
Publicado: (2015)

Effects of butyrate(−) on ruminal Ca(2+) transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels
por: Liebe, Franziska, et al.
Publicado: (2022)

TRPV1 channel-mediated bilateral allodynia induced by unilateral masseter muscle inflammation in rats
por: Simonic-Kocijan, Suncana, et al.
Publicado: (2013)

Divalent Heavy Metal Cations Block the TRPV1 Ca(2+) Channel
por: Pecze, László, et al.
Publicado: (2012)

TRPV4 is the temperature-sensitive ion channel of human sperm
por: Mundt, Nadine, et al.
Publicado: (2018)

Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
por: Gochman, Aaron, et al.
Publicado: (2023)

Biotic and Abiotic Stresses Activate Different Ca(2+) Permeable Channels in Arabidopsis
por: Cao, Xiao-Qiang, et al.
Publicado: (2017)

TRPV1 variants impair intracellular Ca(2+) signaling and may confer susceptibility to malignant hyperthermia
por: Vanden Abeele, Fabien, et al.
Publicado: (2018)

Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca(2+) and Ca(2+)-dependent regulation of TXNIP
por: Zhang, Xiling, et al.
Publicado: (2020)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Influence of glycoprotein MUC1 on trafficking of the Ca(2+)-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis
por: Al-bataineh, Mohammad M., et al.
Publicado: (2023)

Interdomain Interactions Control Ca(2+)-Dependent Potentiation in the Cation Channel TRPV4
por: Strotmann, Rainer, et al.
Publicado: (2010)

TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus
por: Feetham, C H, et al.
Publicado: (2015)

Ca(2+) Permeable AMPA Channels in Diseases of the Nervous System
por: Weiss, John H.
Publicado: (2011)

Role of K(+) and Ca(2+)-Permeable Channels in Osteoblast Functions
por: Kito, Hiroaki, et al.
Publicado: (2021)

An Unorthodox Mechanism Underlying Voltage Sensitivity of TRPV1 Ion Channel
por: Yang, Fan, et al.
Publicado: (2020)

Dihydroceramides Derived from Bacteroidetes Species Sensitize TRPV1 Channels
por: Ludwig, Nora, et al.
Publicado: (2023)

Signaling Between TRPV1/TRPV4 and Intracellular Hydrostatic Pressure in the Mouse Lens
por: Delamere, Nicholas A., et al.
Publicado: (2020)

TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2+)
por: Woolums, Brian M., et al.
Publicado: (2020)

Ryanodine‐sensitive intracellular Ca(2+) channels are involved in the output from the SCN circadian clock
por: Aguilar‐Roblero, Raúl, et al.
Publicado: (2016)

Proton block of proton-activated TRPV1 current
por: Lee, Bo Hyun, et al.
Publicado: (2015)

The oscillation of intracellular Ca(2+) influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium
por: Ihara, Tatsuya, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5uj2u97l285c676b4he9pl6iah