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Identification of human LDHC4 as a potential target for anticancer drug discovery

One of the distinct hallmarks of cancer cells is aerobic glycolysis (Warburg effect). Lactate dehydrogenase A (LDHA) is thought to play a key role in aerobic glycolysis and has been extensively studied, while lactate dehydrogenase C (LDHC), an isoform of LDHA, has received much less attention. Here...

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Detalles Bibliográficos
Autores principales: Tan, Hong, Wang, Huali, Ma, Jinhu, Deng, Hui, He, Qinghua, Chen, Qiang, Zhang, Qinglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136605/
https://www.ncbi.nlm.nih.gov/pubmed/35646544
http://dx.doi.org/10.1016/j.apsb.2021.12.002