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Tetrahedral DNA nanostructures synergize with MnO(2) to enhance antitumor immunity via promoting STING activation and M1 polarization

Stimulator of interferon genes (STING) is a cytosolic DNA sensor which is regarded as a potential target for antitumor immunotherapy. However, clinical trials of STING agonists display limited anti-tumor effects and dose-dependent side-effects like inflammatory damage and cell toxicity. Here, we sho...

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Detalles Bibliográficos
Autores principales: Liang, Siping, Li, Jiaying, Zou, Zhengyu, Mao, Miao, Ming, Siqi, Lin, Fan, Zhang, Ziyan, Cao, Can, Zhou, Jinyu, Zhang, Yuanqing, Li, Jiaping, Wu, Minhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136606/
https://www.ncbi.nlm.nih.gov/pubmed/35646524
http://dx.doi.org/10.1016/j.apsb.2021.12.010