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Tetrahedral DNA nanostructures synergize with MnO(2) to enhance antitumor immunity via promoting STING activation and M1 polarization
Stimulator of interferon genes (STING) is a cytosolic DNA sensor which is regarded as a potential target for antitumor immunotherapy. However, clinical trials of STING agonists display limited anti-tumor effects and dose-dependent side-effects like inflammatory damage and cell toxicity. Here, we sho...
Autores principales: | Liang, Siping, Li, Jiaying, Zou, Zhengyu, Mao, Miao, Ming, Siqi, Lin, Fan, Zhang, Ziyan, Cao, Can, Zhou, Jinyu, Zhang, Yuanqing, Li, Jiaping, Wu, Minhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136606/ https://www.ncbi.nlm.nih.gov/pubmed/35646524 http://dx.doi.org/10.1016/j.apsb.2021.12.010 |
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