Anticarin-β shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis

Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis. The chaperonin T-complex protein ring complex (TRiC) contains eight para...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Gan, Zhang, Min, Meng, Ping, Long, Chengbo, Luo, Xiaodong, Yang, Xingwei, Wang, Yunfei, Zhang, Zhiye, Mwangi, James, Kamau, Peter Muiruri, Dai, Zhi, Ke, Zunfu, Zhang, Yi, Chen, Wenlin, Zhao, Xudong, Ge, Fei, Lv, Qiumin, Rong, Mingqiang, Li, Dongsheng, Jin, Yang, Sheng, Xia, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136613/
https://www.ncbi.nlm.nih.gov/pubmed/35646538
http://dx.doi.org/10.1016/j.apsb.2021.12.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136613/
https://www.ncbi.nlm.nih.gov/pubmed/35646538
http://dx.doi.org/10.1016/j.apsb.2021.12.024

Ejemplares similares