Identification of anthelmintic parbendazole as a therapeutic molecule for HNSCC through connectivity map-based drug repositioning

Head and neck squamous cell carcinoma (HNSCC) is one of the most common human cancers; however, its outcome of pharmacotherapy is always very limited. Herein, we performed a batch query in the connectivity map (cMap) based on bioinformatics, queried out 35 compounds with therapeutic potential, and s...

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Detalles Bibliográficos
Autores principales: Liang, Dong, Yu, Chen, Ma, Zhao, Yang, Xingye, Li, Zhenzhen, Dong, Xuhui, Qin, Xiaojun, Du, Lupei, Li, Minyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136614/
https://www.ncbi.nlm.nih.gov/pubmed/35646536
http://dx.doi.org/10.1016/j.apsb.2021.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136614/
https://www.ncbi.nlm.nih.gov/pubmed/35646536
http://dx.doi.org/10.1016/j.apsb.2021.12.005

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