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Construction of tissue-engineered nucleus pulposus by stimulation with periodic mechanical stress and BMP-2

Intervertebral disc (IVD) degeneration, which is common among elderly individuals, mainly manifests as low back pain and is caused by structural deterioration of the nucleus pulposus (NP) due to physiological mechanical stress. NP mesenchymal stem cells (NPMSCs) around the IVD endplate have multidir...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Gao, Gong-ming, Yang, Kai-yuan, Nong, Lu-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136668/
https://www.ncbi.nlm.nih.gov/pubmed/35633940
http://dx.doi.org/10.1016/j.isci.2022.104405