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Pyrazolone-type compounds: synthesis and in silico assessment of antiviral potential against key viral proteins of SARS-CoV-2

Coronavirus outbreak is still a major public health concern. The high mutation ability of SARS-CoV-2 periodically delivers more transmissible and dangerous variants. Hence, the necessity for an efficient and inexpensive antiviral agent is urgent. In this work, pyrazolone-type compounds were synthesi...

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Detalles Bibliográficos
Autores principales: Branković, Jovica, Milovanović, Vesna M., Simijonović, Dušica, Novaković, Slađana, Petrović, Zorica D., Trifunović, Snežana S., Bogdanović, Goran A., Petrović, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136855/
https://www.ncbi.nlm.nih.gov/pubmed/35733695
http://dx.doi.org/10.1039/d2ra02542f