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Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
The protein TRIM5α has multiple roles in antiretroviral defense, but the mechanisms underlying TRIM5α action are unclear. Here, we employ APEX2-based proteomics to identify TRIM5α-interacting partners. Our proteomics results connect TRIM5 to other proteins with actions in antiviral defense. Addition...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136943/ https://www.ncbi.nlm.nih.gov/pubmed/35545034 http://dx.doi.org/10.1016/j.celrep.2022.110797 |