Phylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics

[Image: see text] The rise and dissemination of glycopeptide antibiotic (GPA)-resistant pathogens in healthcare settings fuel efforts to discover GPAs that can overcome resistance. Members of the type V subclass of GPAs can evade common GPA resistance mechanisms and offer promise as new drug leads....

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Detalles Bibliográficos
Autores principales: Xu, Min, Wang, Wenliang, Waglechner, Nicholas, Culp, Elizabeth J., Guitor, Allison K., Wright, Gerard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136965/
https://www.ncbi.nlm.nih.gov/pubmed/35647273
http://dx.doi.org/10.1021/acscentsci.1c01389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136965/
https://www.ncbi.nlm.nih.gov/pubmed/35647273
http://dx.doi.org/10.1021/acscentsci.1c01389

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