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The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse

BACKGROUND: Hair follicle stem cells (HFSC) play an essential role in the maintenance of hair homeostasis; during the hair cycle, HFSC remain quiescent for most of its duration. The hairpoor mouse (+ /Hr(Hp)), an animal model of Marie-Unna hypotrichosis (MUHH), overexpresses hairless in the bulge, i...

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Detalles Bibliográficos
Autores principales: Choi, Keonwoo, Park, Sang-Hee, Park, Seo-Yeon, Yoon, Sungjoo Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137081/
https://www.ncbi.nlm.nih.gov/pubmed/35619120
http://dx.doi.org/10.1186/s13287-022-02898-w