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(1)H NMR Chemical Exchange Techniques Reveal Local and Global Effects of Oxidized Cytosine Derivatives

[Image: see text] 5-Carboxycytosine (5caC) is a rare epigenetic modification found in nucleic acids of all domains of life. Despite its sparse genomic abundance, 5caC is presumed to play essential regulatory roles in transcription, maintenance and base-excision processes in DNA. In this work, we uti...

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Detalles Bibliográficos
Autores principales: Dubini, Romeo C. A., Korytiaková, Eva, Schinkel, Thea, Heinrichs, Pia, Carell, Thomas, Rovó, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137243/
https://www.ncbi.nlm.nih.gov/pubmed/35637781
http://dx.doi.org/10.1021/acsphyschemau.1c00050