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NIPA (Nuclear Interaction Partner of ALK) Is Crucial for Effective NPM-ALK Mediated Lymphomagenesis

The NPM-ALK fusion kinase is expressed in 60% of systemic anaplastic large-cell lymphomas (ALCL). A Nuclear Interaction Partner of ALK (NIPA) was identified as a binding partner of NPM-ALK. To identify the precise role of NIPA for NPM-ALK-driven lymphomagenesis, we investigated various NPM-ALK(+) ce...

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Detalles Bibliográficos
Autores principales: Kreutmair, Stefanie, Lippert, Lena Johanna, Klingeberg, Cathrin, Albers-Leischner, Corinna, Yacob, Salome, Shlyakhto, Valeria, Mueller, Tony, Mueller-Rudorf, Alina, Yu, Chuanjiang, Gorantla, Sivahari Prasad, Miething, Cornelius, Duyster, Justus, Illert, Anna Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137267/
https://www.ncbi.nlm.nih.gov/pubmed/35646639
http://dx.doi.org/10.3389/fonc.2022.875117