The Impact of Comprehensive Genomic Profiling (CGP) on the Decision-Making Process in the Treatment of ALK-Rearranged Advanced Non-Small Cell Lung Cancer (aNSCLC) After Failure of 2(nd)/3(rd)-Generation ALK Tyrosine Kinase Inhibitors (TKIs)

BACKGROUND: The use of CGP in guiding treatment decisions in aNSCLC with acquired resistance to ALK TKIs is questionable. METHODS: We prospectively assessed the impact of CGP on the decision-making process in ALK-rearranged aNSCLC patients following progression on 2(nd)/3(rd)-generation ALK TKIs. Ph...

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Detalles Bibliográficos
Autores principales: Raphael, Ari, Onn, Amir, Holtzman, Liran, Dudnik, Julia, Urban, Damien, Kian, Waleed, Cohen, Aharon Y., Moskovitz, Mor, Zer, Alona, Bar, Jair, Rabinovich, Natalie Maimon, Grynberg, Shirly, Oedegaard, Cecilie, Agbarya, Abed, Peled, Nir, Shochat, Tzippy, Dudnik, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137396/
https://www.ncbi.nlm.nih.gov/pubmed/35646707
http://dx.doi.org/10.3389/fonc.2022.874712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137396/
https://www.ncbi.nlm.nih.gov/pubmed/35646707
http://dx.doi.org/10.3389/fonc.2022.874712

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