Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum

Tuberous sclerosis complex 1 (TSC1) is a tumor suppressor that promotes the inhibition of mechanistic target of rapamycin (mTOR) pathway, and mutations in TSC1 lead to a rare complex disorder of the same name. Despite phenotype heterogeneity, up to 50% of TSC patients present with autism spectrum di...

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Detalles Bibliográficos
Autores principales: Serra, Ines, Stravs, Ana, Osório, Catarina, Oyaga, Maria Roa, Schonewille, Martijn, Tudorache, Christian, Badura, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137405/
https://www.ncbi.nlm.nih.gov/pubmed/35645731
http://dx.doi.org/10.3389/fnmol.2022.831687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137405/
https://www.ncbi.nlm.nih.gov/pubmed/35645731
http://dx.doi.org/10.3389/fnmol.2022.831687

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