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Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs

Aging is characterized by declines in physiological function that increase risk of age-associated diseases and limit healthspan, mediated in part by chronic low-grade inflammation. Interleukin (IL)-37 suppresses inflammation in pathophysiological states but has not been studied in the context of agi...

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Detalles Bibliográficos
Autores principales: Brunt, Vienna E., Ikoba, Akpevweoghene P., Ziemba, Brian P., Ballak, Dov B., Hoischen, Alexander, Dinarello, Charles A., Ehringer, Marissa A., Seals, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137444/
https://www.ncbi.nlm.nih.gov/pubmed/35622271
http://dx.doi.org/10.1007/s11357-022-00587-3