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Identification of a Novel Inhibitor of TfR1 from Designed and Synthesized Muriceidine A Derivatives
The transferrin receptor 1 (TfR1) plays a key role in cellular iron uptake through its interaction with iron-bound Tf. TfR1 is often reported to be overexpressed in malignant cells, and this increase may be associated with poor prognosis in different types of cancer, which makes it an attractive tar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137542/ https://www.ncbi.nlm.nih.gov/pubmed/35624697 http://dx.doi.org/10.3390/antiox11050834 |