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Identification of a Novel Inhibitor of TfR1 from Designed and Synthesized Muriceidine A Derivatives

The transferrin receptor 1 (TfR1) plays a key role in cellular iron uptake through its interaction with iron-bound Tf. TfR1 is often reported to be overexpressed in malignant cells, and this increase may be associated with poor prognosis in different types of cancer, which makes it an attractive tar...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Ma, Zongchen, Mai, Xiaoyuan, Liu, Xiaoling, Li, Pinglin, Qi, Xin, Li, Guoqiang, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137542/
https://www.ncbi.nlm.nih.gov/pubmed/35624697
http://dx.doi.org/10.3390/antiox11050834