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Identification of a Novel Class of Anti-Melanogenic Compounds, (Z)-5-(Substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one Derivatives, and Their Reactive Oxygen Species Scavenging Activities

The rate-determining role of tyrosinase makes it a critical component in the mechanism that is responsible for melanogenesis. Thirteen (Z)-5-(substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one ((Z)-BPTT) analogs were designed based on the structural features of two potent tyrosinase inhibit...

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Detalles Bibliográficos
Autores principales: Jeong, Yeongmu, Hong, Sojeong, Jung, Hee Jin, Ullah, Sultan, Hwang, YeJi, Choi, Heejeong, Ko, Jeongin, Lee, Jieun, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137581/
https://www.ncbi.nlm.nih.gov/pubmed/35624809
http://dx.doi.org/10.3390/antiox11050948