TXH11106: A Third-Generation MreB Inhibitor with Enhanced Activity against a Broad Range of Gram-Negative Bacterial Pathogens

The emergence of multi-drug-resistant Gram-negative pathogens highlights an urgent clinical need to explore and develop new antibiotics with novel antibacterial targets. MreB is a promising antibacterial target that functions as an essential elongasome protein in most Gram-negative bacterial rods. H...

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Detalles Bibliográficos
Autores principales: Bryan, Eric J., Sagong, Hye Yeon, Parhi, Ajit K., Grier, Mark C., Roberge, Jacques Y., LaVoie, Edmond J., Pilch, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137614/
https://www.ncbi.nlm.nih.gov/pubmed/35625337
http://dx.doi.org/10.3390/antibiotics11050693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137614/
https://www.ncbi.nlm.nih.gov/pubmed/35625337
http://dx.doi.org/10.3390/antibiotics11050693

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