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TXH11106: A Third-Generation MreB Inhibitor with Enhanced Activity against a Broad Range of Gram-Negative Bacterial Pathogens
The emergence of multi-drug-resistant Gram-negative pathogens highlights an urgent clinical need to explore and develop new antibiotics with novel antibacterial targets. MreB is a promising antibacterial target that functions as an essential elongasome protein in most Gram-negative bacterial rods. H...
Autores principales: | Bryan, Eric J., Sagong, Hye Yeon, Parhi, Ajit K., Grier, Mark C., Roberge, Jacques Y., LaVoie, Edmond J., Pilch, Daniel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137614/ https://www.ncbi.nlm.nih.gov/pubmed/35625337 http://dx.doi.org/10.3390/antibiotics11050693 |
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